Emphysema Is-at the Most-Only a Mild Phenotype in the Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension.

The article offers information on the translational research that is essential to develop strategies for the treatment of pulmonary arterial hypertension (PAH) using animal models that reproduce the severity. It mentions that expiratory chest Computed tomography (CT) lung images must be interpreted with caution; and also mentions the absence of hypoxia, can produce an emphysema-like lung phenotype.