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Successful treatment of post‐transplant CMV meningoencephalitis with third‐party CMV virus‐specific T cells: Lessons learned.

Authors :
Alonso, Laura
Rudilla, Francesc
Gimeno, Ramón
Codinach, Margarita
Blanco, Margarita
Querol, Sergio
Diaz de Heredia, Cristina
Source :
Pediatric Transplantation; Dec2019, Vol. 23 Issue 8, pN.PAG-N.PAG, 1p
Publication Year :
2019

Abstract

Cytomegalovirus encephalitis is a challenging life‐threatening complication following hematopoietic stem cell transplantation for which medical treatment is usually ineffective or toxic. However, in recent years, adoptive T‐cell therapy has been reported to provide a significant chance of cure for patients with viral infections. Herein, two cases of pediatric patients successfully treated with third‐party donor‐derived virus‐specific T cells for CMV meningoencephalitis are reported. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13973142
Volume :
23
Issue :
8
Database :
Complementary Index
Journal :
Pediatric Transplantation
Publication Type :
Academic Journal
Accession number :
139862331
Full Text :
https://doi.org/10.1111/petr.13584