Back to Search Start Over

Bacopa monnieri , a Neuroprotective Lead in Alzheimer Disease: A Review on Its Properties, Mechanisms of Action, and Preclinical and Clinical Studies.

Authors :
Abdul Manap, Aimi Syamima
Vijayabalan, Shantini
Madhavan, Priya
Chia, Yoke Yin
Arya, Aditya
Wong, Eng Hwa
Rizwan, Farzana
Bindal, Umesh
Koshy, Shajan
Source :
Drug Target Insights; 2019, Vol. 13, pN.PAG-N.PAG, 1p
Publication Year :
2019

Abstract

Alzheimer disease is a neurodegenerative disease that is signified by cognitive decline, memory loss, and erratic behavior. Till date, no cure for Alzheimer exists and the current Alzheimer medications have limited effectiveness. However, herbal medicines may slow down the disease's progression, which may hopefully reduce the number of cases in the years to come. Numerous studies have been done on characterizing the neuroprotective properties from plants belonging to Scrophulariaceae family, particularly Bacopa monnieri and its polyphenolic compounds known as bacosides. This review presents the findings on bacosides in therapeutic plants and their impact on Alzheimer disease pathology. These reports present data on the clinical, cellular activities, phytochemistry, and biological applications that may be used in new drug treatment for Alzheimer disease. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
11773928
Volume :
13
Database :
Complementary Index
Journal :
Drug Target Insights
Publication Type :
Academic Journal
Accession number :
139430825
Full Text :
https://doi.org/10.1177/1177392819866412