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The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management.

Authors :
Alfarouk, Khalid O.
Bashir, Adil H. H.
Aljarbou, Ahmed N.
Ramadan, AbdelRahman M.
Muddathir, Abdel Khalig
AlHoufie, Sari T. S.
Hifny, Abdelhamid
Elhassan, Gamal O.
Ibrahim, Muntaser E.
Alqahtani, Saad S.
AlSharari, Shakir D.
Supuran, Claudiu T.
Rauch, Cyril
Cardone, Rosa Angela
Reshkin, Stephan J.
Fais, Stefano
Harguindey, Salvador
Source :
Frontiers in Oncology; 2/22/2019, p1-12, 12p
Publication Year :
2019

Abstract

Helicobacter pylori (HP) is a facultative anaerobic bacterium. HP is a normal flora having immuno-modulating properties. This bacterium is an example of a microorganism inducing gastric cancer. Its carcinogenicity depends on bacteria-host related factors. The proper understanding of the biology of HP inducing gastric cancer offers the potential strategy in the managing of HP rather than eradicating it. In this article, we try to summarize the biology of HP-induced gastric cancer and discuss the current pharmacological approach to treat and prevent its carcinogenicity. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
2234943X
Database :
Complementary Index
Journal :
Frontiers in Oncology
Publication Type :
Academic Journal
Accession number :
138960266
Full Text :
https://doi.org/10.3389/fonc.2019.00075