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Ways Forward for Tolerance-Inducing Cellular Therapies- an AFACTT Perspective.

Authors :
ten Brinke, Anja
Martinez-Llordella, Marc
Cools, Nathalie
Hilkens, Catharien M. U.
van Ham, S. Marieke
Sawitzki, Birgit
Geissler, Edward K.
Lombardi, Giovanna
Trzonkowski, Piotr
Martinez-Caceres, Eva
Source :
Frontiers in Immunology; 2/22/2019, p1-20, 20p
Publication Year :
2019

Abstract

Clinical studies with cellular therapies using tolerance-inducing cells, such as tolerogenic antigen-presenting cells (tolAPC) and regulatory T cells (Treg) for the prevention of transplant rejection and the treatment of autoimmune diseases have been expanding the last decade. In this perspective, we will summarize the current perspectives of the clinical application of both tolAPC and Treg, and will address future directions and the importance of immunomonitoring in clinical studies that will result in progress in the field. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16643224
Database :
Complementary Index
Journal :
Frontiers in Immunology
Publication Type :
Academic Journal
Accession number :
138960210
Full Text :
https://doi.org/10.3389/fimmu.2019.00181