Evaluating the Biological Applications of Myristica fragrans Seeds for Bactericidal and Cytotoxic Effects.

Introduction: Bioactive compounds from herbal plants possess a wide range of pharmaceutical activities and one among them is Myristica fragrans (Nutmeg). Aim: Antibacterial screening of the different solvent extracted phytoconstituents showed maximum growth inhibitory effect against E.coli and S. mutans. Agar well diffusion sensitivity testing method was adopted for this study. Method: Acetone extract of the seeds also performed good bactericidal effect against the bacterial pathogens. Result: MTT assay also demonstrated good cytotoxic effect against MCF-7 cell lines in a dose-dependent manner with inhibitory concentration (IC₅₀) achieved at 62.5 μg/mL. Conclusion: Based on the findings of the study, seeds of Myristica fragrans could be exploited in developing potential bioactive pharmaceutical drugs for effective treatment of cancer. [ABSTRACT FROM AUTHOR]