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Water-soluble diboronic acid-based fluorescent sensors recognizing D-sorbitol.
- Source :
- New Journal of Chemistry; 9/21/2019, Vol. 43 Issue 35, p13802-13809, 8p
- Publication Year :
- 2019
-
Abstract
- Herein, several boronic acid-based sensors were reported selectively recognizing D -sorbitol in aqueous solution. The fluorescence of sensor 15c was enhanced by 1.5-fold when combined with a low concentration of D -sorbitol (8.88 μM), and the fluorescence enhanced by 0.6-fold after binding to D -fructose, while it did not change obviously when combined with other carbohydrates, including D -arabinose, D -galactose, D -mannose, D -ribose, D -maltose, D -xylose, D -glucose and D -glucosamine. Fluorescence tests were carried out in DMSO/PBS (pH 9, 0.1 M) solution (1 : 99, v/v), at room temperature, which indicated that the sensors are water-soluble. In addition, competition studies showed that sensor 15c works well as a D -sorbitol-specific fluorescence sensor in both the absence and presence of carbohydrate interferents. And sensor 15c has a high binding constant (10 922 ± 776 M<superscript>−1</superscript>) and a low limit of detection (6.91 × 10<superscript>−7</superscript> M) at pH 9 among the investigated sensors toward D -sorbitol. Furthermore, sensor 15c was applied to the analysis of real samples (D -sorbitol for oral administration). These studies indicated that sensor 15c may serve as a potential tool to detect the content of D -sorbitol in drugs and food products. [ABSTRACT FROM AUTHOR]
- Subjects :
- MONOSACCHARIDES
MALTOSE
DETECTORS
BINDING constant
AQUEOUS solutions
DETECTION limit
Subjects
Details
- Language :
- English
- ISSN :
- 11440546
- Volume :
- 43
- Issue :
- 35
- Database :
- Complementary Index
- Journal :
- New Journal of Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 138522192
- Full Text :
- https://doi.org/10.1039/c9nj02636c