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High resolution profiling of X chromosomal aberrations by array comparative genomic hybridisation.

Authors :
Veltman, J.A.
Yntema, H.G.
Lugtenberg, D.
Arts, H.
Briault, S.
Huys, E.H.L.P.G.
Osoegawa, K.
de Jong, P.
Brunner, H.G.
van Kessel, A. Geurts
van Bokhoven, H.
Schoenmakers, E.F.P.M.
Source :
Journal of Medical Genetics; Jun2004, Vol. 41 Issue 6, p425-432, 8p, 1 Chart, 3 Graphs
Publication Year :
2004

Abstract

Explains that medical genetics researchers have constructed, validated, and applied a full coverage chromosome X BAC array for array based comparative genomic hybridization array. 25 percent of mental retardation in males is due to genetic defect linked to X chromosome; High resolution copy number screening in the search for MRX genes.

Details

Language :
English
ISSN :
00222593
Volume :
41
Issue :
6
Database :
Complementary Index
Journal :
Journal of Medical Genetics
Publication Type :
Academic Journal
Accession number :
13818047
Full Text :
https://doi.org/10.1136/jmg.2004.018531