Back to Search
Start Over
Metal-Free Promoted CF2/CF3-Difunctionalization of Unactivated Alkenes.
- Source :
- Advanced Synthesis & Catalysis; 6/18/2019, Vol. 361 Issue 12, p2945-2950, 6p
- Publication Year :
- 2019
-
Abstract
- An operationally simple radical difluoroalkylation/trifluoromethylation and alkynylation of unactivated alkenes under mild conditions has been developed. Through this protocol, a series of CF<subscript>2</subscript>/CF<subscript>3</subscript>-substituted linear alkynyl ketones were synthesized via a unique 1,2-alkynyl radical migration. Notably, no transition-metal catalyst is needed in the developed reaction system, and excellent functional group compatibility was observed. [ABSTRACT FROM AUTHOR]
- Subjects :
- ALKENES
FUNCTIONAL groups
KETONES
Subjects
Details
- Language :
- English
- ISSN :
- 16154150
- Volume :
- 361
- Issue :
- 12
- Database :
- Complementary Index
- Journal :
- Advanced Synthesis & Catalysis
- Publication Type :
- Academic Journal
- Accession number :
- 137675648
- Full Text :
- https://doi.org/10.1002/adsc.201900231