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One-step templated synthesis of chiral organometallic salicyloxazoline complexes.
- Source :
- BMC Chemistry; 4/4/2019, Vol. 13 Issue 1, pN.PAG-N.PAG, 1p
- Publication Year :
- 2019
-
Abstract
- Background: The general approach to the synthesis of metal complexes begins with ligand synthesis, followed by ligand reaction with metal salts to afford organometallic complexes. Our research group first reported a one-pot multicomponent synthesis of chiral oxazolinyl–zinc complexes, in the presence of a large amount of ZnCl<subscript>2</subscript> (0.4–2.6 equiv.), with the yields of some products reaching 90%. Results: Our prior strategy was extended to use copper, cobalt, nickel, manganese, palladium or platinum salts as the third component. The one-step method used 1.0 equivalent of a metal salt, such as M(OAc)<subscript>2</subscript>·nH<subscript>2</subscript>O or MCl<subscript>2</subscript>·nH<subscript>2</subscript>O (M: Cu, Co, Ni, Pd or Pt, n = 1, 2 or 4), as a reagent to generate chiral salicyloxazoline complexes 1–8 in the reaction of 2-cyanophenol with different d- and l-amino alcohols. Conclusion: Complexes 1–8 were obtained using a one-pot method with a sequential strategy. The reaction outcome was demonstrated for three-component reactions between metal salts, amino alcohols and 2-hydroxybenzonitrile to afford organometallic complexes in good yields (65–95%). [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 2661801X
- Volume :
- 13
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- BMC Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 137445189
- Full Text :
- https://doi.org/10.1186/s13065-019-0565-z