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Examined and positive lymph nodes counts and lymph nodes ratio are associated with survival in major salivary gland cancer.
- Source :
- Head & Neck; Aug2019, Vol. 41 Issue 8, p2625-2635, 11p
- Publication Year :
- 2019
-
Abstract
- Background: We aimed to investigate the prognostic role of examined (dissected) lymph nodes (ELNs), negative LNs (NLNs), and positive (metastatic) LNs (PLNs) counts and LN ratio (LNR = PLNs/ELNs×100) in patients with major salivary gland cancer (SGC). Methods: Data were retrieved for major SGC patients diagnosed between 1988 and 2011 from Surveillance, Epidemiology, and End Results program. Results: We have included 5446 patients with major SGC. Most patients had parotid gland cancer (84.61%). Patients having >18 ELNs, >4 PLNs, and >33.33% LNR were associated with a worse survival. Moreover, older age, male patients, grade IV, distant stage, unmarried patients, submandibular gland cancer, and received chemotherapy but not received surgery were significantly associated with a worse survival. Conclusions: We demonstrated that patients with >18 ELNs and >4 PLNs counts, and >33.33% LNR were high‐risk group patients. We strongly suggest adding the ELNs and PLNs counts and/or LNR into the current staging system. [ABSTRACT FROM AUTHOR]
- Subjects :
- SALIVARY gland cancer
LYMPH nodes
SUBMANDIBULAR gland
PAROTID glands
Subjects
Details
- Language :
- English
- ISSN :
- 10433074
- Volume :
- 41
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- Head & Neck
- Publication Type :
- Academic Journal
- Accession number :
- 137436434
- Full Text :
- https://doi.org/10.1002/hed.25742