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Radiation effects of nuclear physics rays on hepatoma cells.

Authors :
Wenhui Zhao
Lu Cong
Guerrero-Sánchez, Yolanda
Source :
Open Physics; Jan2019, Vol. 17 Issue 1, p167-176, 10p
Publication Year :
2019

Abstract

The traditional method of cloning formation is used to study the radiation effect of nuclear physics rays on hepatoma cells, and the results obtained are not reliable. Therefore, a new method of studying the radiation effect of nuclear physics rays on hepatoma cells is proposed. PCC method is used to study the radiation effect ofγ-rays on hepatoma cells. Radiation effects of X-rays on hepatoma cells were studied by radionuclide formation assay, neutral comet electrophoresis and γH2AX focal detection. The results showed that the survival curves of HepG2 hepatoma cells irradiated byγ-rays were well fitted by linear squares. There was a linear relationship between the survival rate and irradiation dose of HepG2 hepatoma cells irradiated byγ-rays. HepG2 hepatoma cells showed strong tolerance to X-ray irradiation, and the positive rate of H2AX cells reached 100% in each dose group only 0.5 h after X-ray irradiation. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
23915471
Volume :
17
Issue :
1
Database :
Complementary Index
Journal :
Open Physics
Publication Type :
Academic Journal
Accession number :
137156935
Full Text :
https://doi.org/10.1515/phys-2019-0017