Pd-catalysed selective C(sp3)–H arylation and acetoxylation of alcohols.

A palladium catalyzed selective C(sp³)–H arylation and acetoxylation of alcohols using a practical bidentate auxiliary were developed. Masked alcohols were selectively arylated at the β-position with diverse aryl iodides for the first time. Moreover, an efficient and site-selective acetoxylation of various primary methyl, methylene, and benzylic C(sp³)–H bonds was performed by using cheap K₂S₂O₈ as the external oxidant. [ABSTRACT FROM AUTHOR]