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Placental Histology After Minor Trauma in Pregnancy: A Pilot Study.

Authors :
van der Knoop, BJ
van der Voorn, JP
Nikkels, PGJ
Zonnenberg, IA
van Weissenbruch, MM
Vermeulen, RJ
de Vries, JIP
Source :
Pediatric & Developmental Pathology; May/Jun2019, Vol. 22 Issue 3, p221-228, 8p
Publication Year :
2019

Abstract

Objective: Trauma in pregnancy may cause placental abruption. Consequences of moderate placental injury on neurodevelopment are unknown. The aim was to evaluate placental histology after maternal trauma. Methods: A prospective study was conducted at 2 tertiary medical centers in the Netherlands. Placentas from women exposed to maternal trauma ≥ 20 weeks' gestational age were histologically examined. Neurological follow-up of the infants was performed at 1 year of age by means of Alberta Infant Motor Scale. Histological findings were compared to placentas from pregnancies without trauma. Principal Results: Thirteen placentas were investigated in the trauma group. The control group consisted of 15 placentas. Placental pathology was seen more often in the trauma cases (11 of the 13) than in the controls (6 of the 15), P =.024. Neurological follow-up was normal. Conclusions: In this small population, majority of the placentas showed pathology after minor trauma in pregnancy without consequences for neurodevelopment at 1 year. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10935266
Volume :
22
Issue :
3
Database :
Complementary Index
Journal :
Pediatric & Developmental Pathology
Publication Type :
Academic Journal
Accession number :
136890323
Full Text :
https://doi.org/10.1177/1093526618799292