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A Retrospective Cohort Study of Risk Factors for Surgical Site Infection Following Liver Transplantation.
- Source :
- Progress in Transplantation; Jun2019, Vol. 29 Issue 2, p144-149, 6p
- Publication Year :
- 2019
-
Abstract
- Background: Surgical site infection is an important complication in the postoperative period among liver transplant recipients. However, little is known about the risk factors in this patient group. Therefore, the objective of this study was to analyze the incidence and risk factors for surgical site infections among adult liver transplant recipients. Methods: Medical records of adult liver transplant recipients from January 1, 2009, to December 31, 2015, were analyzed in this retrospective cohort study. Results: We enrolled 156 recipients' medical records. Forty-two (26.9%) cases of surgical site infections were identified. The main isolated microorganisms were methicillin-resistant Staphylococcus species, extended spectrum β-lactamase-producing Klebsiella species, carbapenem-resistant Pseudomonas aeruginosa, carbapenem-resistant Acinetobacter baumannii, and vancomycin-susceptible Enterococcus faecalis. We found that long operative times (≥487 minutes) and differences in body mass index between donor and recipient (≥1.3 kg/m<superscript>2</superscript>) increased the risk for surgical site infections by approximately 5 times (odds ratio [OR], 5.5; 95% confidence interval [CI], 2.5-11.8), and capillary glycemia ≥175 mg/dL in the first 96 postoperative hours increased the risk by approximately 3 times (OR, 2.97; 95% CI, 1.43-6.17). Conclusions: There was a high incidence of surgical site infections among the studied population and that some risk factors identified differ from those reported in the scientific literature. [ABSTRACT FROM AUTHOR]
- Subjects :
- CHI-squared test
CONFIDENCE intervals
STATISTICAL correlation
ENTEROCOCCUS
FISHER exact test
KLEBSIELLA
LIVER transplantation
LONGITUDINAL method
MEDICAL records
PSEUDOMONAS
REGRESSION analysis
RESEARCH funding
SURGICAL site infections
TIME
TRANSPLANTATION of organs, tissues, etc.
BODY mass index
DISEASE incidence
RETROSPECTIVE studies
METHICILLIN-resistant staphylococcus aureus
DATA analysis software
ODDS ratio
MANN Whitney U Test
DISEASE risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 15269248
- Volume :
- 29
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Progress in Transplantation
- Publication Type :
- Academic Journal
- Accession number :
- 136890102
- Full Text :
- https://doi.org/10.1177/1526924819835831