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Health economic analysis of a cluster-randomised trial (OptiBIRTH) designed to increase rates of vaginal birth after caesarean section.
- Source :
- BJOG: An International Journal of Obstetrics & Gynaecology; Jul2019, Vol. 126 Issue 8, p1043-1051, 9p, 1 Diagram, 1 Chart, 1 Graph
- Publication Year :
- 2019
-
Abstract
- <bold>Objective: </bold>To perform a health economic analysis of an intervention designed to increase rates of vaginal birth after caesarean, compared with usual care.<bold>Design: </bold>Economic analysis alongside the cluster-randomised OptiBIRTH trial (Optimising childbirth by increasing vaginal birth after caesarean section (VBAC) through enhanced women-centred care).<bold>Setting: </bold>Fifteen maternity units in three European countries - Germany (five), Ireland (five), and Italy (five) - with relatively low VBAC rates.<bold>Population: </bold>Pregnant women with a history of one previous lower-segment caesarean section; sites were randomised (3:2) to intervention or control.<bold>Methods: </bold>A cost-utility analysis from both societal and health-services perspectives, using a decision tree.<bold>Main Outcome Measures: </bold>Costs and resource use per woman and infant were compared between the control and intervention group by country, from pregnancy recognition until 3 months postpartum. Based on the caesarean section rates, and maternal and neonatal morbidities and mortality, the incremental cost-utility ratios were calculated per country.<bold>Results: </bold>The mean difference in costs per quality-adjusted life years (QALYs) gained from a societal perspective between the intervention and the control group, using a probabilistic sensitivity analysis, was: €263 (95% CI €258-268) and 0.008 QALYs (95% CI 0.008-0.009 QALYs) for Germany, €456 (95% CI €448-464) and 0.052 QALYs (95% CI 0.051-0.053 QALYs) for Ireland, and €1174 (95% CI €1170-1178) and 0.006 QALYs (95% CI 0.005-0.007 QALYs) for Italy. The incremental cost-utility ratios were €33,741/QALY for Germany, €8785/QALY for Ireland, and €214,318/QALY for Italy, with a 51% probability of being cost-effective for Germany, 92% for Ireland, and 15% for Italy.<bold>Conclusion: </bold>The OptiBIRTH intervention was likely to be cost-effective in Ireland and Germany.<bold>Tweetable Abstract: </bold>The OptiBIRTH intervention (to increase VBAC rates) is likely to be cost-effective in Germany and Ireland. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14700328
- Volume :
- 126
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- BJOG: An International Journal of Obstetrics & Gynaecology
- Publication Type :
- Academic Journal
- Accession number :
- 136838673
- Full Text :
- https://doi.org/10.1111/1471-0528.15673