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Immune cell therapy for hepatocellular carcinoma.

Authors :
Mizukoshi, Eishiro
Kaneko, Shuichi
Source :
Journal of Hematology & Oncology; 5/29/2019, Vol. 12 Issue 1, pN.PAG-N.PAG, 1p
Publication Year :
2019

Abstract

Given the success of immune checkpoint inhibitors and chimeric antigen receptor (CAR) T cells in clinical settings, the host immune system plays an important role in the recognition and targeting of tumor cells in cancer immunotherapy. As a result, there have been numerous advancements in immune cell therapy using human immune cells. However, recent evidence suggests that one type of immunotherapy alone is not effective for the treatment of cancer, particularly solid tumors. Thus, effective immunotherapy combinations, such as the combination of checkpoint inhibitors and immune cell therapy, are needed. This review focuses on hepatocellular carcinoma among other solid tumors and discusses the current status and future of immune cell therapy in cancer immunotherapy. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17568722
Volume :
12
Issue :
1
Database :
Complementary Index
Journal :
Journal of Hematology & Oncology
Publication Type :
Academic Journal
Accession number :
136713971
Full Text :
https://doi.org/10.1186/s13045-019-0742-5