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A clinical audit of the growth of preterm infants fed predominantly pasteurised donor human milk v. those fed mother's own milk in the neonatal intensive care unit.
- Source :
- British Journal of Nutrition; 5/14/2019, Vol. 121 Issue 9, p1018-1025, 8p
- Publication Year :
- 2019
-
Abstract
- Preterm infants whose mothers are unable to produce sufficient breast milk are increasingly being supplemented with pasteurised donor human milk (PDHM) instead of commercial preterm infant formula. Concerns have been raised that this practice can result in reduced growth. This retrospective clinical audit collected data from the medical records of a cohort of preterm infants (≤30 weeks gestational age) receiving either ≥28 d of PDHM (n 53) or ≥28 d of their mother's own milk (MOM, n 43) with standard fortification supplied to both groups during admission. Weight growth velocity was assessed from regained birth weight to 34+1 weeks' postmenstrual age (PMA); and weight, length and head circumference were compared at discharge and 12 months (corrected age). At 34+1 weeks' PMA, the weight growth velocity (g/kg per d) was significantly lower in the PDHM group (15·4 g/kg per d, 95 % CI 14·6, 16·1) compared with the MOM group (16·9 g/kg per d, 95 % CI 16·1, 17·7, P =0·007). However, the increase was still within clinically acceptable limits (>15 g/kg per d) and no significant difference was observed in the weight between the two groups. There was no significant difference in weight between the groups at discharge or at the 12-month corrected gestational age review. Although we demonstrated a significant reduction in the weight growth velocity of preterm infants receiving PDHM at 34 weeks' PMA, this difference is not present at discharge, suggesting that the growth deficit is reduced by supplementation before discharge. [ABSTRACT FROM AUTHOR]
- Subjects :
- AUDITING
BODY weight
BREAST milk
COMPARATIVE studies
CONFIDENCE intervals
ORGAN donation
HUMAN growth
PREMATURE infants
INFANT development
LONGITUDINAL method
MOTHERS
NEONATAL intensive care
REFERENCE values
BREAST milk collection & preservation
FOOD pasteurization
NEONATAL intensive care units
RETROSPECTIVE studies
DESCRIPTIVE statistics
CHILDREN
Subjects
Details
- Language :
- English
- ISSN :
- 00071145
- Volume :
- 121
- Issue :
- 9
- Database :
- Complementary Index
- Journal :
- British Journal of Nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 136253764
- Full Text :
- https://doi.org/10.1017/S0007114519000357