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Two new phenylspirodrimanes from the deep-sea derived fungus Stachybotrys sp. MCCC 3A00409.
- Source :
- Natural Product Research; Feb2019, Vol. 33 Issue 3, p386-392, 7p
- Publication Year :
- 2019
-
Abstract
- Two new phenylspirodrimanes, stachybotrin H (1) and stachybotrysin H (9) together with eleven known analogues (2–8, 10–13) were isolated from deep-sea derived Stachybotrys sp. MCCC 3A00409. Their structures were determined by extensive NMR data and mass spectroscopic analysis. Compounds 9–12 showed weak cytotoxicity against three human cancer cell lines K562, Hela and HL60 with IC<subscript>50</subscript> in the range of 18.5–52.8 μM. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14786419
- Volume :
- 33
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Natural Product Research
- Publication Type :
- Academic Journal
- Accession number :
- 135802296
- Full Text :
- https://doi.org/10.1080/14786419.2018.1455041