Back to Search
Start Over
Cushing's syndrome--an epidemiological study based on a canine population of 21,281 dogs.
- Source :
- Open Veterinary Journal; 2019, Vol. 9 Issue 1, p27-32, 6p
- Publication Year :
- 2019
-
Abstract
- The epidemiological characteristics of spontaneous hypercortisolism (HC) were derived from 21,281 client-owned dogs selected from four private veterinary clinics and one university reference center for endocrinology. The odds ratio (OR) method was employed to investigate the risk of developing HC related to breed, gender, and sexual status. The estimated prevalence of HC in the four private clinics was 0.20% [95% confidence interval (CI), 0.13-0.27] and was significantly different compared to the university reference center (1.46%; 95% CI, 1.12-1.80). Sex, breed, and age resulted in risk factors for HC. Mean (± SD) age for dogs with HC was 9.8 (± 2.5) yr. Females had higher risk for HC compared to males (OR 1.85; 95% CI, 1.24-2.75); all neutered dogs (both males and females) had higher risk than intact dogs (OR 2.54; 95% CI, 1.72-3.73); and neutered females had higher risk compared to intact females (OR 2.61; 95% CI, 1.54-4.42). Using the mixed breed dogs as a control population (OR = 1), the risk of developing HC was significantly higher in the Standard Schnauzer (OR 58.1; p < 0.0001) and Fox Terrier (OR 20.33; p < 0.0001). With regard to HC, this study identified an overall prevalence of 0.20%. The data support the existence of sex predisposition, with the highest risk for neutered females. [ABSTRACT FROM AUTHOR]
- Subjects :
- CUSHING'S syndrome
DOGS
DOG breeds
ODDS ratio
Subjects
Details
- Language :
- English
- ISSN :
- 22264485
- Volume :
- 9
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Open Veterinary Journal
- Publication Type :
- Academic Journal
- Accession number :
- 135619712
- Full Text :
- https://doi.org/10.4314/ovj.v9i1.5