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Early mitral inflow velocity to left ventricular global strain ratio predicts limited exercise capacity.
- Source :
- Echocardiography; Mar2019, Vol. 36 Issue 3, p503-511, 9p
- Publication Year :
- 2019
-
Abstract
- Background: Estimation of left ventricular filling pressure (LVFP) is the essential part of the echocardiographic workup for exercise intolerance. The ratio of the mitral early filling velocity to the left ventricular global longitudinal strain (E/LVGLS) has emerged as a novel index of LVFP. This study aimed to investigate the relationship between E/LVGLS and exercise capacity. Methods and results: We retrospectively reviewed 90 patients with exertional dyspnea who underwent echocardiography and cardiopulmonary exercise test. Patients were classified into three groups according to their percent‐predicted maximal oxygen consumption (ppVo2) (G ≧ 75, ppVo2 > 75%, n = 20; G 50‐75, ppVo2 75‐50%, n = 57; G < 50, ppVo2 < 50%, n = 13). Measurements were (a) the relationship between ppVo2 and E/LVGLS and (b) the efficiency of integrated diastolic assessment using E/LVGLS, left ventricular volume, mitral annular early diastolic velocity (E′), and tricuspid regurgitation to identify the patient with impaired exercise capacity. Univariate linear regression analysis demonstrated that E/LVGLS had significant correlation with ppVo2 (ρ = 0.52, P < 0.001). The area under the ROC of E/LVGLS for ppVo2 < 50% was 0.86 (95%CI 0.75‐0.97). The DeLong test showed that E/LVGLS was efficient to detect ppVo2 < 50% than E/E′ (P = 0.007). When used in the integrated assessment of LVFP as the alternative for E/E′, E/LVGLS improved risk classification for impaired exercise capacity. Conclusion: E/LVGLS may be a more efficient index than E/E′ to identify exercise impairment as a single index and as a part of the integrated diastolic assessment. [ABSTRACT FROM AUTHOR]
- Subjects :
- MITRAL valve
HEART ventricle diseases
BLOOD flow measurement
BLOOD pressure
CARDIAC output
CARDIOPULMONARY system
CARDIOVASCULAR diseases risk factors
CONFIDENCE intervals
DYSPNEA
ECHOCARDIOGRAPHY
EXERCISE tests
CARDIAC patients
LEFT heart ventricle
HEART ventricles
HEMODYNAMICS
REGRESSION analysis
STATISTICS
TRICUSPID valve
OXYGEN consumption
RETROSPECTIVE studies
RECEIVER operating characteristic curves
DESCRIPTIVE statistics
EXERCISE tolerance
PHYSIOLOGY
Subjects
Details
- Language :
- English
- ISSN :
- 07422822
- Volume :
- 36
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Echocardiography
- Publication Type :
- Academic Journal
- Accession number :
- 135293424
- Full Text :
- https://doi.org/10.1111/echo.14263