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Drug Repurposing Campaigns for Human Cytomegalovirus Identify a Natural Compound Targeting the Immediate-Early 2 (IE2) Protein: A Comment on "The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts".

Authors :
Mercorelli, Beatrice
Luganini, Anna
Palù, Giorgio
Gribaudo, Giorgio
Loregian, Arianna
Source :
Viruses (1999-4915); Feb2019, Vol. 11 Issue 2, p117, 1p
Publication Year :
2019

Abstract

The article discusses the human cytomegalovirus (HCMV) as a major opportunistic pathogen for immunocompromised individuals. The virus caused mortality and morbidity with congenital defects due to lacking of an effective vaccine. The article also discusses the three independent drug directed against HCMV.

Details

Language :
English
ISSN :
19994915
Volume :
11
Issue :
2
Database :
Complementary Index
Journal :
Viruses (1999-4915)
Publication Type :
Academic Journal
Accession number :
134963619
Full Text :
https://doi.org/10.3390/v11020117