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Finding the needle in a haystack: Mapping antifungal drug resistance in fungal pathogen by genomic approaches.
- Source :
- PLoS Pathogens; 1/31/2019, Vol. 15 Issue 1, p1-9, 9p
- Publication Year :
- 2019
-
Abstract
- The article discusses antifungal resistance in plant and human fungal pathogens with a special focus on genome-wide studies. It mentions that resistance mechanisms can be grouped in three general principles including decrease of effective intracellular drug concentration, alterations of the drug target, and compensatory mechanisms which decrease drug toxicity.
Details
- Language :
- English
- ISSN :
- 15537366
- Volume :
- 15
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- PLoS Pathogens
- Publication Type :
- Academic Journal
- Accession number :
- 134396136
- Full Text :
- https://doi.org/10.1371/journal.ppat.1007478