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Conservation Analysis Showing High Variability in the Rate of Evolution of Regeneration-related Genes.
- Source :
- AIP Conference Proceedings; 2019, Vol. 2058 Issue 1, p020045-1-020045-6, 6p, 6 Charts, 1 Graph
- Publication Year :
- 2019
-
Abstract
- Schmidtea mediterranea has a high regeneration ability. Previous studies have discovered genes contributing to this species’ regeneration ability, including genes with orthologs in human. However, no previous comparative studies have investigated these orthologs across a diversity of species. Understanding how the regeneration-related genes evolved in a diverse range of extant species is helpful to both the biological and medical field. Here I reported conservation measurements, pairwise dN/dS, of regeneration-related genes generated from 12 species against human. I then compared them to the pairwise dN/dS of housekeeping under the same criteria and found that the evolution process of genes related to regeneration varies across species and was less conserved than the housekeeping genes, indicating a less evolutionary constraint over regeneration-related genes. [ABSTRACT FROM AUTHOR]
- Subjects :
- REGENERATION (Biology)
GENES
GENOMES
BIOLOGY
CELLS
Subjects
Details
- Language :
- English
- ISSN :
- 0094243X
- Volume :
- 2058
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- AIP Conference Proceedings
- Publication Type :
- Conference
- Accession number :
- 134076428
- Full Text :
- https://doi.org/10.1063/1.5085558