Determination of the Inhibitory Power Exerted by Copper (II) Complexes Derived from of the Schiff Bases Against to Certain Fungal Species of Fusarium.

The fungi of the genus Fusarium include several phyto-pathogenic species capable of attacking a large number of plants, causing diseases called fusarioses. We investigated the antifungal activity on this type of fungus. We examined in vitro a series of copper (II) complexes derivatives that were differently substituted into groups; Electron-donating or electron-withdrawing against three fungal strains: Fusarium culmorum, Fusarium graminearum and Fusarium verticillioides. Using the agar dilution method to determine the inhibitory power exerted by these complexes at a concentration of 1 mg / ml and hymexazol was used as a standard fungicide. The results show that the highest mycelia inhibition of the fungal strains is carried out for the complex [Cu-(SA-p-Cl)2] with a 42.57 ± 0.63% inhibition against the species Fusarium graminearum. However, low activity was revealed for the complex [Cu-(SA-o-Cl)2] at inhibitory power of 6.41 ± 0.35%. We have noted that the copper (II) complexes with the para-substituted Schiff bases represent a better activity against the Fusarium culmorum, F. graminearum and F. verticillioides strains. The diversity of antifungal activity is influenced by the presence of the various substituted groups (methyl, methoxy, chloro and nitro) on the structure of the copper (II) complexes examined. [ABSTRACT FROM AUTHOR]