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Epidemiology of fungaemia in Sweden: A nationwide retrospective observational survey.
- Source :
- Mycoses; Oct2018, Vol. 61 Issue 10, p777-785, 9p
- Publication Year :
- 2018
-
Abstract
- Summary: Objectives: To identify the epidemiology and antifungal susceptibilities of Candida spp. among blood culture isolates to identify the epidemiology and antifungal susceptibilities of Candida spp. among blood culture isolates in Sweden. Methods: The study was a retrospective, observational nationwide laboratory‐based surveillance for fungaemia and fungal meningitis and was conducted from September 2015 to August 2016. Results: In total, 488 Candida blood culture isolates were obtained from 471 patients (58% males). Compared to our previous study, the incidence of candidaemia has increased from 4.2/100 000 (2005‐2006) to 4.7/100 000 population/year (2015‐2016). The three most common Candida spp. isolated from blood cultures were Candida albicans (54.7%), Candida glabrata (19.7%) and species in the Candida parapsilosis complex (9.4%). Candida resistance to fluconazole was 2% in C. albicans and between 0% and 100%, in non‐albicans species other than C. glabrata and C. krusei. Resistance to voriconazole was rare, except for C. glabrata, C. krusei and C. tropicalis. Resistance to anidulafungin was 3.8% while no Candida isolate was resistant to amphotericin B. Conclusions: We report an overall increase in candidaemia but a minor decrease of C. albicans while C. glabrata and C. parapsilosis remain constant over this 10‐year period. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09337407
- Volume :
- 61
- Issue :
- 10
- Database :
- Complementary Index
- Journal :
- Mycoses
- Publication Type :
- Academic Journal
- Accession number :
- 131949309
- Full Text :
- https://doi.org/10.1111/myc.12816