Multiplicity‐edited 1H‐1H TOCSY experiment.

Authors :: Nolis, Pau
Parella, Teodor
Source :: Magnetic Resonance in Chemistry; Oct2018, Vol. 56 Issue 10, p976-982, 7p
Publication Year :: 2018
Abstract: A <superscript>1</superscript>H‐<superscript>1</superscript>H total correlation spectroscopy (TOCSY) experiment incorporating <superscript>13</superscript>C multiplicity information is proposed. In addition, broadband <superscript>1</superscript>H homodecoupling in the indirect dimension can be implemented using a perfect BIRD module that affords exclusive <superscript>1</superscript>H chemical shift evolution with full decoupling of all heteronuclear and homonuclear (including <superscript>2</superscript>J<subscript>HH</subscript>) coupling constants. As a complement to the normal TOCSY and the recent PSYCHE‐TOCSY experiments, this novel multiplicity‐edited TOCSY experiment distinguishes between CH/CH<subscript>3</subscript> (phased up) and CH<subscript>2</subscript> (phased down) cross‐peaks, which facilitates resonance analysis and assignment. [ABSTRACT FROM AUTHOR]