Whole Genome MBD‐seq reveals different CpG methylation patterns in Azacytidine‐treated Juvenile Myelomonocytic Leukaemia (JMML) patients.

The article looks at a study which evaluates impact of azacytidine treatment on aberrant DNA methylation in Juvenile Myelomonocytic Leukaemia (JMML) patients. Topics discussed include membrane elements such as adhesion molecules, developmental processes and cell cycle-related genes, assessment and genomic DNA extraction and sequence analysis and scenario of pathogenetic epigenetic regulation and specific levels of hypermethylation.