Long-term clinical results of the Metasul metal-on-metal total hip arthroplasty: 12.6 years follow-up of 128 primary total hip replacements.

Introduction: The purpose of the present study is to report the long-term clinical results of an uncemented total hip arthroplasty (THA) using a Metasul metal-on-metal (MoM) 28-mm bearing and to evaluate the long-term serum cobalt levels. Methods: At an average of 12.6 years following primary THA, we retrospectively reviewed the clinical results of the first 116 consecutive patients (128 THAs) in our institution who underwent 28-mm Metasul MoM THA. Of the 78 patients who were able to visit our outpatient clinic, serum cobalt levels were evaluated. Results: The overall survival rate of the cohort was 96.1% (95% confidence interval [CI], 93.2-99.6), 12.6 years (95% CI, 12.3-12.7 years) following surgery. 3 patients had undergone revision due to aseptic loosening of the stem and 2 patients sustained a periprosthetic fracture. The average modified Harris Hip Score was 90 (72-97) and the average Oxford Hip Score was 56 (48-60), representing both excellent outcome scores. The average serum cobalt of the entire cohort was 20.1 nmol/L (range 8.5-227.7 nmol/L). Serum cobalt levels of patients with a bilateral MoM THA were significantly higher (35.0 nmol/l, p<0.01). No relation between serum cobalt levels, subjective outcome, radiolucent lines on radiographs and survivorship of the implant was noted. Conclusions: Long-term results of the metasul MoM bearing articulation in THA seem to be excellent, although cobalt serum levels should be monitored closely. [ABSTRACT FROM AUTHOR]