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Evaluating the Impact and Benefits of Fluticasone Furoate/Vilanterol in Individuals with Asthma or COPD: A Mixed-Methods Analysis of Patient Experiences.
- Source :
- Advances in Therapy; Sep2018, Vol. 35 Issue 9, p1378-1399, 22p
- Publication Year :
- 2018
-
Abstract
- <bold>Introduction: </bold>This study evaluated patients' experiences with fluticasone furoate/vilanterol (FF/VI) combination therapy in UK patients with asthma or chronic obstructive pulmonary disease (COPD).<bold>Methods: </bold>Participants aged ≥ 18 years, with self-reported, physician-diagnosed asthma or COPD (≥ 1 year) who had been receiving FF/VI (≥ 3 months) were recruited from UK primary care. This two-phase, mixed-methods study consisted of a semi-structured, telephone-interview phase (qualitative) and a self-completed online/paper-survey phase (quantitative).<bold>Results: </bold>The telephone-interview phase included 50 individuals [asthma, n = 25; COPD, n = 25; mean age (SD) 56.7 years (13.3); 50% female]. Of these, 21 with asthma reported that their condition was stable/well controlled and 13 with COPD felt their condition was manageable. Most participants found FF/VI easy to use (asthma, 25; COPD, 23), easy to integrate into their daily routine (asthma, 25; COPD, 24), and able to control symptoms for ≥ 24 h (asthma, 14; COPD, 16). During the survey phase, 199 individuals were recruited [asthma, n = 100; COPD, n = 99; mean age (SD) 63.6 years (15.1); 59.3% female]. Most participants were satisfied/very satisfied with the efficacy of FF/VI in terms of all-day symptom relief (asthma, 84%; COPD, 75%) and found FF/VI easy/very easy to fit into their daily routine (asthma, 99%; COPD, 96%), easy/very easy to use (asthma, 97%; COPD, 92%), and convenient/very convenient to take as instructed (asthma, 95%; COPD, 93%). Significantly more individuals with asthma (87% versus 46%, P < 0.001) and numerically more individuals with COPD (84% versus 76%, P = 0.055) were satisfied/very satisfied with FF/VI compared with their most recent previous maintenance medication.<bold>Conclusion: </bold>The majority of individuals in this study had confidence in FF/VI and were satisfied or very satisfied with various key attributes of the treatment.<bold>Trial Registration: </bold>GSK study HO-15-15503/204888.<bold>Funding: </bold>GSK. [ABSTRACT FROM AUTHOR]
- Subjects :
- STEROID drugs
DRUG therapy for asthma
ALCOHOLS (Chemical class)
BRONCHODILATOR agents
COMBINATION drug therapy
COMPARATIVE studies
DRUG administration
OBSTRUCTIVE lung diseases
RESEARCH methodology
MEDICAL cooperation
RESEARCH
RESEARCH funding
STEROIDS
EVALUATION research
TREATMENT effectiveness
BLIND experiment
BENZENE derivatives
INHALATION administration
FORCED expiratory volume
Subjects
Details
- Language :
- English
- ISSN :
- 0741238X
- Volume :
- 35
- Issue :
- 9
- Database :
- Complementary Index
- Journal :
- Advances in Therapy
- Publication Type :
- Academic Journal
- Accession number :
- 131497508
- Full Text :
- https://doi.org/10.1007/s12325-018-0760-7