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Responsiveness of EQ-5D in Patients With a Distal Radius Fracture.
- Source :
- HAND; Sep2018, Vol. 13 Issue 5, p572-580, 9p
- Publication Year :
- 2018
-
Abstract
- Background: The EuroQol Group 5-Dimension (EQ-5D) questionnaire is frequently used as an outcome measure of general patient-reported health-related quality of life (HRQoL). We evaluated the internal and external responsiveness of EQ-5D (specifically EQ-5D<subscript>index</subscript> score) in patients with a surgically treated distal radius fracture. Methods: Within the context of a randomized controlled trial (RCT), 132 patients with a surgically treated distal radius fracture filled out EQ-5D and Patient-Rated Wrist Evaluation (PRWE-Swe) at baseline (preinjury state), and at 3 and 12 months. Internal responsiveness was evaluated by calculating mean change score and standardized response mean (SRM) of the EQ-5D<subscript>index</subscript> scores. External responsiveness was evaluated with PRWE-Swe as the external criterion. PRWE-Swe was used to define 4 subgroups of patients with different clinical outcomes. The ability of EQ-5D<subscript>index</subscript> change score to discriminate between these subgroups was analyzed with logistic regression, receiver operating characteristic (ROC) curves, and area under the ROC curves (AUROCs). Correlation analysis was made with Spearman’s ρ test. Results: The mean change in EQ-5D<subscript>index</subscript> score from baseline to the 3-month follow-up was −16.1 and from the 3- to the 12-month follow-up was 7.6. The corresponding SRMs were large (0.93) and small to moderate (0.47). Analysis of external responsiveness displayed odds ratios >1 and AUROCs between 0.70 and 0.76 in all 4 subgroups. The proportion of patients correctly classified into the 4 subgroups by the EQ-5D<subscript>index</subscript> change scores was 78% to 94%. Spearman’s ρ was 0.35. Conclusion: EQ-5D displayed an overall acceptable to good responsiveness in patients with a distal radius fracture. It may thus be used as a measure of HRQoL in this patient group. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15589447
- Volume :
- 13
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- HAND
- Publication Type :
- Academic Journal
- Accession number :
- 131407493
- Full Text :
- https://doi.org/10.1177/1558944717725378