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Attitudes of physicians from 10 European countries on adherence and how treatment modalities in ABSSSI affect adherence: results from a Delphi survey.

Authors :
Stargardt, Tom
Eckmann, Christian
Bouza, Emilio
Rossolini, Gian Maria
Grossi, Paolo Antonio
Source :
European Journal of Clinical Microbiology & Infectious Diseases; Sep2018, Vol. 37 Issue 9, p1611-1618, 8p
Publication Year :
2018

Abstract

To explore the attitudes of European physicians on adherence and how treatment modalities impact adherence in complicated forms of soft skin and skin structure infections, now referred as acute bacterial skin and skin structures infections (ABSSSI). After literature review, a questionnaire was prepared. Topics focused on (1) the importance of adherence, (2) the importance of administration regimen on adherence, (3) the importance of drug selection on adherence, (4) the importance of complexity on choice of drug for treatment, (5) the role of adherence in drug resistance, and (6) the role of adherence in administration of long-acting antibiotics (ABs). The questionnaire was administered to 323 European infectious diseases specialists, of whom 74% responded. A modified Delphi method was used to obtain the highest consensus. Results varied by countries. We found a high degree of agreement of the importance of adherence in ABSSSI treatment. Experts agreed that complexity of patient’s conditions, drug selection, drug resistance, the type of regimen, and the number of infusions impact adherence. Two items linking oral switching and adherence did not reach consensus. Adherence for ABSSSI therapies appears a crucial factor for therapeutic management and reduces the risk of AB resistance. Among new treatment opportunities, long-acting agents, with their characteristics, may represent an interesting options. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09349723
Volume :
37
Issue :
9
Database :
Complementary Index
Journal :
European Journal of Clinical Microbiology & Infectious Diseases
Publication Type :
Academic Journal
Accession number :
131394929
Full Text :
https://doi.org/10.1007/s10096-018-3264-0