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Canine spinal meningiomas and nerve sheath tumours in 34 dogs (2008‐2016): Distribution and long‐term outcome based upon histopathology and treatment modality.

Authors :
Lacassagne, K.
Hearon, K.
Berg, J.
Séguin, B.
Hoyt, L.
Byer, B.
Selmic, L. E.
Source :
Veterinary & Comparative Oncology; Sep2018, Vol. 16 Issue 3, p344-351, 8p
Publication Year :
2018

Abstract

The purpose of this retrospective, multicentre case series was to describe the outcome following surgery and/or radiation of spinal meningiomas and nerve sheath tumours (NSTs) based upon treatment modality, with a specific aim to evaluate the survival times and time to recurrence following treatment for each histopathological diagnosis. Our hypothesis was that the addition of radiation therapy modalities to treatment will yield longer time to recurrence of clinical signs and survival time. Thirty‐four dogs met the inclusion criteria of histopathologically diagnosed extramedullary spinal meningioma or NST. Sixteen extramedullary spinal meningiomas and 18 NSTs were diagnosed. A diagnosis of meningioma was associated with a significantly longer survival time compared with NSTs, with median survival times (MST) of 508 days (95% confidence interval [CI]: 66‐881) vs 187 days (95% CI: 76‐433; P = .02). Dogs (seven) treated with stereotactic radiation therapy (SRT) for recurrence after surgery alone or SRT alone as their initial treatment gained an additional 125 to 346 days survival time. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14765810
Volume :
16
Issue :
3
Database :
Complementary Index
Journal :
Veterinary & Comparative Oncology
Publication Type :
Academic Journal
Accession number :
131134742
Full Text :
https://doi.org/10.1111/vco.12385