A new steroidal saponin from Polygonatum sibiricum.

Authors :: Zhang, Hong-Yang
Hu, Wei-Cheng
Ma, Guo-Xu
Zhu, Nai-Liang
Sun, Xiao-Bo
Wu, Hai-Feng
Xu, Xu-Dong
Source :: Journal of Asian Natural Products Research; Jun2018, Vol. 20 Issue 6, p586-592, 7p
Publication Year :: 2018
Abstract: A new furostan type steroidal saponin, kingianoside Z (1), along with four known compounds (2-5), was isolated from the ethanolic extract of Polygonatum sibiricum Delar. ex Redoute. Their structures were determined by spectroscopical method and by comparison with previously reported spectroscopic data. Compounds 3-5 showed significant cytotoxicity against HepG2 cell lines with IC<subscript>50</subscript> values of 14.2, 12.1 and 8.5 μM, respectively. [ABSTRACT FROM AUTHOR]