A new bischromanone from the stems of Semecarpus caudata.

Authors :: Dang, Phu H.
Nguyen, Tinh T.
Le, Tho H.
Nguyen, Hai X.
Nguyen, Mai T. T.
Nguyen, Nhan T.
Source :: Natural Product Research; Aug2018, Vol. 32 Issue 15, p1745-1750, 6p
Publication Year :: 2018
Abstract: From an CHCl<subscript>3</subscript>-soluble fraction of the stems of Semecarpus caudata, one new bischromanone named semecarpanone (1), together with 5 known flavonoids (2'6) were isolated. Their structures were elucidated based on interpretation of spectroscopic data. The stereo-configuration of 1 was identified based on the calculated and experimental coupling constants. Compounds 4'6 showed potent tyrosinase inhibitory activity with the IC<subscript>50</subscript> values ranging from 15.0 to 76.3 μM. [ABSTRACT FROM AUTHOR]