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A growth factor-dependent nuclear kinase phosphorylates p27Kip1 and regulates cell cycle progression.
- Source :
- EMBO Journal; 7/1/2002, Vol. 21 Issue 13, p3390-3401, 12p
- Publication Year :
- 2002
-
Abstract
- The cyclin-dependent kinase inhibitor, p27<superscript>Kip1</superscript>, which regulates cell cycle progression, is controlled by its subcellular localization and subsequent degradation. p27<superscript>Kip1</superscript> is phosphorylated on serine 10 (S10) and threonine 187 (T1 [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 02614189
- Volume :
- 21
- Issue :
- 13
- Database :
- Complementary Index
- Journal :
- EMBO Journal
- Publication Type :
- Academic Journal
- Accession number :
- 12955937
- Full Text :
- https://doi.org/10.1093/emboj/cdf343