PHYSIOLOGICAL AND PATHOHISTOLOGICAL CHANGES OF COMMON CARP (CYPRINUS CARPIO) TEATED WITH CARBAMYL.

The present study aims to study physiological and Pathohistological changes in tissue and blood of common carp Cyprinus carpio via exposure to different concentration of Carbamyl pesticide (0.1, 0.5 and 1 mg/l) for 96 hour, the results showed GOT activity in blood were significantly increased in the dose (0.1 and 0.5 mg/L) and decreased in dose (1 mg/l). While the activity of glutamate pyruvate transaminase GPT, Cholesterol concentration, Lactate dehydrogenase activity LDH and TG concentration were significantly elevatedin three dose (0.1, 0.5 and 1 mg/l). The pathohistological effects of carbamyl, liver tissue with marked intracellular glycogenosis appearing as a single cytoplasmic vacuole with centrally located nuclei. Portal tracts are normally oriented with no evidence of inflammatory cell infiltrate or interface activity, gastric wall showing gastric glands with normal architecture, cerebral cortex showing mild subpialoedema and mild cerebral oedema marked by periastrocytic halo, cerebellar tissue, showing moderate congestion of subpial blood vessels (small arrows), with normal ependymal lining of fourth ventricle, Cerebral tissue with moderate subpialoedemaandCerebellar tissue with normal granular layer appearing as small round blue cells on the left lower corner with normal Purkinje cells. [ABSTRACT FROM AUTHOR]