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Study on acute toxicity of anti-vertigo granule on mice.

Authors :
Wen, Zhonghua
Hao, Shaojun
Xie, Guoqi
Li, Jun
Su, Feng
Liu, Xiaobin
Wang, Xidong
Zhang, Zhengchen
Trincone, Antonio
Azevedo, Joao L.
Gong, Mingfu
Source :
AIP Conference Proceedings; 2018, Vol. 1956 Issue 1, pN.PAG-N.PAG, 2p
Publication Year :
2018

Abstract

To observe the effect of anti - glare particles on acute toxicity of mice. Methods: 40 male and female mice weighing 18 - 21 g were randomly divided into anti - glare granule group and normal saline control group. The maximum volume of anti - glare particles (0.94 g/ml) was administered before the experiment. Results: the oral toxicity of the suspension was very small. The maximal concentration of mice was given at the maximum volume of gastric perfusion, and it was given three times in 1st. The cumulative maximum tolerance dose was 112.8g/kg per day. The dose was 226 times of clinical dosage and no death was found in mice. Conclusion: the toxicity of Kangxuan granules is very small and it can be considered safe in clinical use. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0094243X
Volume :
1956
Issue :
1
Database :
Complementary Index
Journal :
AIP Conference Proceedings
Publication Type :
Conference
Accession number :
129330940
Full Text :
https://doi.org/10.1063/1.5034293