EFFECT OF DIODE LASER-ACTIVATED ANTIMICROBIAL AGENTS (LAAAS) ON PATHOGENIC BACTERIA.

Laser-activated antimicrobial agents (LAAAS) are drugs that have no antimicrobial activity in the dark but can be activated by laser of an appropriate wavelength. The effect of photosensitizers (silver nanoparticle, Methylene blue Dye) was studied by the presence and absence of laser on two types of gram positive (Staphylococcus aureus) and negative (Pseudomonas aeruginosa) bacteria. The work was in several stages where the first stage was without the use of laser, which is divided in turn to the effect of dye only, the effect of nanoparticles only, the joint effect of dye and nanoparticles. The second phase was on the same format used previously but added to the effect of low power diode laser. Our results showed that the effective antibacterial of silver nanoparticle; (methylene blue) and combined between them were differenced, P. aeruginosa more sensitivity than Staphylococcus aureus, so AgNPs was more effective against gram positive bacteria than gram negative bacterial strain. [ABSTRACT FROM AUTHOR]