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A simple “mix-and-detection” method for the sensitive detection of telomerase from cancer cells under absolutely isothermal conditions.

Authors :
Ma, Fei
Wei, Shu-hua
Leng, Junhong
Tang, Bo
Zhang, Chun-yang
Source :
Chemical Communications; 3/11/2018, Vol. 54 Issue 20, p2483-2486, 4p
Publication Year :
2018

Abstract

We develop a simple “mix-and-detection” method for the sensitive detection of telomerase from cancer cells under absolutely isothermal conditions. This method enables one-step and one-tube detection of telomerase with a detection limit of 3 cells, and it can be further applied for the screening of telomerase inhibitors and the discrimination of cancer cells from normal cells. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
TELOMERASE
CANCER cells

Details

Language :
English
ISSN :
13597345
Volume :
54
Issue :
20
Database :
Complementary Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
128324372
Full Text :
https://doi.org/10.1039/c8cc00093j