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Discrimination of FCGR2B polymorphism without coamplification of FCGR2A and FCGR2C genes.

Authors :
Bonatti, F.
Adorni, A.
Percesepe, A.
Martorana, D.
Source :
International Journal of Immunogenetics; Feb2018, Vol. 45 Issue 1, p22-25, 4p
Publication Year :
2018

Abstract

The FCGR locus is characterized by high polymorphism and sequence homology. In particular, the Ile232Thr polymorphism in the FCGR2B gene results in inaccurate genotyping in most published papers. The purpose of the study was to develop an accurate genotyping assay able to discriminate this polymorphism. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
GENETIC polymorphisms
NUCLEOTIDE sequencing
GENOTYPES
SINGLE nucleotide polymorphisms
GENETICS of disease susceptibility
PHARMACOGENOMICS

Details

Language :
English
ISSN :
17443121
Volume :
45
Issue :
1
Database :
Complementary Index
Journal :
International Journal of Immunogenetics
Publication Type :
Academic Journal
Accession number :
127191558
Full Text :
https://doi.org/10.1111/iji.12351
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