Hb A 2 -Tianhe ( HBD : c.323G>A): First Report in a Chinese Family with Normal Hb A 2 -β-Thalassemia Trait.

Coinheritance of δ-globin variants along with β-globin gene defects can interfere with correct diagnosis of β-thalassemia (β-thal) trait. In this report, we present the coinheritance of a δ-globin variant, Hb A2-Tianhe [δ107(G9)Gly→Asp;HBD: c.323G>A] and a heterozygous β-thal in a Chinese individual with microcytosis, hypochromia and a normal Hb A2level. [ABSTRACT FROM AUTHOR]