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Two New Lipoxygenase Inhibiting Constituents from Pervoskia abrotanoides.
- Source :
- Journal of the Chemical Society of Pakistan; Dec2017, Vol. 39 Issue 6, p1084-1088, 5p
- Publication Year :
- 2017
-
Abstract
- In the present work two new compounds have been isolated from the whole plant of Pervoskia abrotanoides. The structures were elucidated by the extensive use of sophisticated spectroscopic techniques (¹HNMR, <superscript>13</superscript>C-NMR, HMQC, HMBC, ¹H-¹H COSY, NOESY, EIMS, HREIMS, and IR). The structures were characterized as cholest-4,9(11)-diene-2α,3β-diol, 1 and 22α-hydroxy-12-oleanen-3-one, 2. Both the compounds 1 and 2 showed promising inhibitory activity against lipoxygenase enzyme. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 02535106
- Volume :
- 39
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Journal of the Chemical Society of Pakistan
- Publication Type :
- Academic Journal
- Accession number :
- 127027270