Integrating RNA Expression Identifies Candidate Gene for Orofacial Clefts.

The article discusses the genes that act as risk factors for orofacial clefts (OFCs), including cleft lip and cleft palate, through using a study on RNA expression. The role that mesenchymal stem cells play in regulating OFCs is discussed. An overview of single-nucleotide polymorphisms' (SNPs') control of gene expression, including in regard to the use of expression quantitative trait loci (eQTLs) mapping, is provided.