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Accurate Determination of Gold Nanorods Concentrations from Optoacoustic Signals Detected at 870nm and 905 nm by Using High-Power Diode Lasers with Fast Switching Electronics.
- Source :
- Progress in Electromagnetics Research B; 2017, Vol. 78, p143-154, 12p
- Publication Year :
- 2017
-
Abstract
- Optoacoustic imaging (OAI) is an emerging biomedical technique that allows visualization of in-depth tissues by using ultrasonic signals generated by short laser pulses. In this work, the authors combine the optical power of several pulsed high-power diode lasers (HPDLs) at 870 nm and 905 nm to a 7-to-1 675-µm fiber bundle to generate optoacoustic (OA) signals from different mixtures of two gold nanorods solutions with absorbance peak at ~ 860 nm and ~ 900 nm, respectively. The pulses produced to generate OA signals are alternated between the two wavelengths by a microcontroller circuit with fast switching (0.5ms). From the amplitude of the OA signals, the concentrations of the nanoparticles solutions are easily estimated with high accuracy using a fluence model. The results achieved with the proposed system show very good agreement between the concentrations of gold nanorods estimated from measurements and the expected values. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 19376472
- Volume :
- 78
- Database :
- Complementary Index
- Journal :
- Progress in Electromagnetics Research B
- Publication Type :
- Academic Journal
- Accession number :
- 126228573
- Full Text :
- https://doi.org/10.2528/pierb17080810