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Disease Burden of Clostridium difficile Infections in Adults, Hong Kong, China, 2006-2014.
- Source :
- Emerging Infectious Diseases; Oct2017, Vol. 23 Issue 10, p1671-1679, 9p, 5 Charts, 2 Graphs
- Publication Year :
- 2017
-
Abstract
- Cross-sectional studies suggest an increasing trend in incidence and relatively low recurrence rates of Clostridium difficile infections in Asia than in Europe and North America. The temporal trend of C. difficile infection in Asia is not completely understood. We conducted a territory-wide population-based observational study to investigate the burden and clinical outcomes in Hong Kong, China, over a 9-year period. A total of 15,753 cases were identified, including 14,402 (91.4%) healthcare-associated cases and 817 (5.1%) community-associated cases. After adjustment for diagnostic test, we found that incidence increased from 15.41 cases/100,000 persons in 2006 to 36.31 cases/100,000 persons in 2014, an annual increase of 26%. This increase was associated with elderly patients, for whom incidence increased 3-fold over the period. Recurrence at 60 days increased from 5.7% in 2006 to 9.1% in 2014 (p<0.001). Our data suggest the need for further surveillance, especially in Asia, which contains ≈60% of the world's population. [ABSTRACT FROM AUTHOR]
- Subjects :
- CLOSTRIDIUM diseases
CLOSTRIDIOIDES difficile
DISEASE incidence
OLDER people
DISEASES in older people
COMPARATIVE studies
CROSS infection
EPIDEMIOLOGY
RESEARCH methodology
MEDICAL cooperation
RESEARCH
SURVIVAL analysis (Biometry)
DISEASE relapse
EVALUATION research
COMMUNITY-acquired infections
CROSS-sectional method
Subjects
Details
- Language :
- English
- ISSN :
- 10806040
- Volume :
- 23
- Issue :
- 10
- Database :
- Complementary Index
- Journal :
- Emerging Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 125252208
- Full Text :
- https://doi.org/10.3201/eid2310.170797