Antibacterial Effect of Provisional Cements with Incorporated Polyethyleneimine Nanoparticles: An In Vivo Study.

<bold>Purpose: </bold>Provisional restorations exhibit various degrees of microleakage when cemented. Incorporation of quaternized polyethyleneimine nanoparticles (QPEI) into provisional cements may be effective against bacteria in vivo.<bold>Materials and Methods: </bold>Nine polymethylmethacrylate provisional restorations in human volunteers were evaluated after cementation with and without QPEI nanoparticles. Bacterial load in the provisional cement was assessed after 1 week of cementation.<bold>Results: </bold>The number of colony-forming units in the cement with QPEI was significantly lower (P < .05) than in the control cement.<bold>Conclusion: </bold>The results of this in vivo study clearly indicate that provisional cement incorporating QPEI nanoparticles significantly reduces viable bacterial counts in the provisional cement in all patients. [ABSTRACT FROM AUTHOR]