Effectiveness and adverse effects of radical radiotherapy on patients aged 90 or above.

Purpose: In recent years, there were reports that adults and elderly individuals exhibit similar rates of tumor control, treatment success, and side effects. We aim to evaluate the effects of radical radiation therapy on people aged 90 years or above. Materials and Methods: Radiotherapy for radical cure purposes was administered on 25 patients. A dose of 60 Gy/30 fraction was given to 20 of the 25 patients. The other doses given were 30 Gy/5 fraction to one patient with skin cancer; SBRT at 52 Gy/4 fraction and 48 Gy/4 fraction, respectively, to two patients with lung cancer; 40 Gy/20 fraction to one patient with plasmacytoma; and 39 Gy/13 fraction to one patient with pancreatic cancer. For the assessment of treatment response, the RECIST. Adverse event was estimated on the basis of the CTCAE. Results: All 25 patients were able to finish the treatment. The average age was 93.1, with a larger population of women than that of men. Radiotherapy with curative intent provided complete response + partial response in 24 cases. Conclusion: Among elderly cancer patients aged 90 years or above, particularly those with skin cancer, the response rate was high. No adverse events higher than grade 2 were observed. [ABSTRACT FROM AUTHOR]