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The Impact of Frailty on Patient-Centered Outcomes Following Aortic Valve Replacement.
- Source :
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences; Jul2017, Vol. 72 Issue 7, p917-921, 5p, 2 Charts, 1 Graph
- Publication Year :
- 2017
-
Abstract
- <bold>Background: </bold>Frailty confers risk for surgical morbidity and mortality. Whether patient-reported measures of health, well-being, or quality of life respond differently to surgery in non-frail and frail individuals is unknown.<bold>Methods: </bold>Older adults with severe aortic stenosis presenting for surgery were assessed for frailty using Cardiovascular Health Study Criteria. Patient-reported measures of functional capacity (Duke Activity Status Index [DASI]), physical and mental health (Medical Outcomes Study Short Form-Physical and Mental Component Scales [SF-12 PCS and SF-12 MCS, respectively]), well-being (linear analogue self-assessment [LASA]), and quality of life (LASA) were administered before and 3 months after surgery.<bold>Results: </bold>Of 103 participants (mean age of 80.6 years), 54 were frail. Frail participants had lower baseline DASI, SF-12 PCS, SF-12 MCS, physical well-being, and quality of life scores than non-frail participants. At follow-up, frail participants showed significant improvement in physical function, with DASI and SF-12 PCS scores improving by 50% and 14%, respectively. Non-frail subjects did not significantly improve in these measures. SF-12 MCS scores also improved to a greater extent in frail compared to non-frail participants (3.6 vs < 1 point). Furthermore, the frail participants improved to a greater extent than non-frail participants in physical well-being (21.6 vs 7.1 points) and quality of life measures (25.1 vs 8.7 points).<bold>Conclusions: </bold>Frailty is prevalent in older adults with severe aortic stenosis and is associated with poor physical and mental function, physical well-being, and quality of life. In response to surgery, frail participants exhibited greater improvement in these patient-centered outcomes than non-frail peers. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10795006
- Volume :
- 72
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 123424037
- Full Text :
- https://doi.org/10.1093/gerona/glx038