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Synthesis of 2-Substituted Quinolines via Rhodium(III)-Catalyzed C-H Activation of Imidamides and Coupling with Cyclopropanols.
- Source :
- Advanced Synthesis & Catalysis; 5/17/2017, Vol. 359 Issue 10, p1620-1625, 6p
- Publication Year :
- 2017
-
Abstract
- An efficient synthesis of 2-substituted quinolines from readily available cyclopropanols and imidamides has been developed, where the cyclopropanol acts as a C<subscript>3</subscript> synthon. With the assistance of a bifunctional imidamide directing group, the reaction occurred via sequential C-H/C-C cleavage and C-C/C-N bond formation. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 16154150
- Volume :
- 359
- Issue :
- 10
- Database :
- Complementary Index
- Journal :
- Advanced Synthesis & Catalysis
- Publication Type :
- Academic Journal
- Accession number :
- 123088910
- Full Text :
- https://doi.org/10.1002/adsc.201601278